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Хімічні та біологічні науки
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Відділення біохімії, фізіології та молекулярної біології
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Biopolymers and Cell
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Вiopolymers and Cell, 2011, vol. 27
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Вiopolymers and Cell, 2011, №. 5
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Перегляд Вiopolymers and Cell, 2011, №. 5 за назвою

Перегляд Вiopolymers and Cell, 2011, №. 5 за назвою

Результати 1-20 з 20

Association of mitochondrial lysyl-tRNA synthetase with HIV-1 GagPol involves catalytic domain of the synthetase and transframe and integrase domains of Pol

Kobbi, L.; Dias, J.; Octobre, G.; Comisso, M.; Kaminska, M.; Shalak, V.F.; Mirande, M. (Вiopolymers and Cell, 2011)

Aim. Analyze the interaction between Lysyl-tRNA synthetase (LysRS) and HIV-1 GagPol to know whether a particular N-terminal sequence of mitochondrial LysRS triggers a specific recognition with GagPol. Methods. Yeast ...
Brain plasticity of rats exposed to prenatal immobilization stress

Abrahamyan, S.S.; Meliksetyan, I.B.; Sahakyan, I.K.; Tumasyan, N.V.; Badalyan, B.Yu.; Galoyan, A.A. (Вiopolymers and Cell, 2011)

Aim. This histochemical and immunohistochemical study was aimed at examining the brain cellular structures of newborn rats exposed to prenatal immobilization (IMO) stress. Methods. Histochemical method on detection of ...
Brain plasticity of rats exposed to prenatal immobilization stress

Abrahamyan, S.S.; Meliksetyan, I.B.; Sahakyan, I.K.; Tumasyan, N.V.; Badalyan, B.Yu.; Galoyan, A.A. (Вiopolymers and Cell, 2011)

Aim. This histochemical and immunohistochemical study was aimed at examining the brain cellular structures of newborn rats exposed to prenatal immobilization (IMO) stress. Methods. Histochemical method on detection of ...
Characterization and vectorization of siRNA targeting RET/PTC1 in human papillary thyroid carcinoma cells

Massade, L. (Вiopolymers and Cell, 2011)

RET/PTC1 fusion oncogene is the most common genetic alteration identified to date in thyroid papillary carcinomas (PTC) and represents a good target forsmall interfering RNA (siRNA). Our aim was: i) to target the RET/PTC1 ...
Disturbances in lipid second messengers generation by stimulated blood lymphocytes in breast cancer

Lazyan, M.P.; Davtyan, H.H.; Batikyan, T.B.; Kazaryan, R.A.; Alexanyan, K.A.; Galstyan, H.M.; Tadevosyan, Yu.V. (Вiopolymers and Cell, 2011)

Aim. The main objective of thisstudy wasthe comparative investigation of diverse lipid second messenger(LSM) generation by human peripheral blood lymphocytes (HPBL) at different (5, 10, 30 and 60 s) time points of ...
Dynamic nature of active chromatin hubs

Gavrilov, A.A.; Philonenko, E.S.; Iarovaia, O.V.; Razin, S.V. (Вiopolymers and Cell, 2011)

Aim. In order to get more information about organization of active chromatin hubs and their role in the regulation of gene transcription we have studied the spatial organization of the a-globin gene domain in cultured chicken ...
Effect of proline-rich polypeptide on various lines of tumour cells, normal bone marrow and giantcell tumour stromal tissue

Chailakhyan, R.K.; Galoyan, A.A.; Gerasimov, Yu.V.; Stepanova, E.V.; Chailakhyan, M.R.; Solomko, E.Sh. (Вiopolymers and Cell, 2011)

The aim of the study was to assess the effect of proline-rich polypeptide (PRP) on bone marrow stromal stem cells in vivo and in vitro and on tumour cell lines. Methods. Isolation of giant-cell tumour (GCT) stromal ...
FSHD myoblasts fail to downregulate intermediate filament protein vimentin during myogenic differentiation

Dmitriev, P.V.; Barat, A.L.; Cochet, E.; Ogryzko, V.V.; Laoudj-Chenivesse, D.; Vassetzky, Y.S.; Lipinski, M. (Вiopolymers and Cell, 2011)

Facioscapulohumeral muscular dystrophy (FSHD) is an autosomal dominant hereditary neuromuscular disorder. The clinical features of FSHD include weakness of the facial and shoulder girdle muscles followed by wasting of ...
Interaction of PARP2 with DNA structures mimicking DNA repair intermediates

Kutuzov, M.M.; Ame, J.-C.; Khodyreva, S.N.; Schreiber, V.; Lavrik, O.I. (Вiopolymers and Cell, 2011)

Poly(ADP-ribosyl)ation is a posttranslational protein modification significant for the genomic stability and cell survival in response to DNA damage. Poly(ADP-ribosyl)ation is catalyzed by poly(ADP-ribose)polymerases (PARPs). ...
IV International Meeting «Early Events in Human Pathologies»

Galoyan, A.A.; Vassetzky, Y.S. (Вiopolymers and Cell, 2011)

The meeting «Early Events in Human Pathologies» held in Yerevan (Republica of Armenia) on October 12–16, 2011 will unite Armenian, Ukrainian, Russian, and French scientists working on cancer, neurodegenerative and ...
IV International Meeting «Early Events in Human Pathologies» (12–16 October 2011 Yerevan, Republic of Armenia)

Автор відсутній (Вiopolymers and Cell, 2011)
Mutations in MEFV cause alterations in neutrophil F-actin and phagocytosis dynamics

Davtyan, T.K.; Avetisyan, S.A.; Hakobyan, G.S. (Вiopolymers and Cell, 2011)

Aim. To examine neutrophil F-actin, phagocytosis and macropinocytosis dymanics in patients with Familial Mediterranean Fever (FMF), in an effort to understand the mechanisms that regulate switch of neutrophil activation ...
Parameters оf cytokine regulation as additional criterion of immunodiagnosis

Ter-Pogosyan, Z.R. (Вiopolymers and Cell, 2011)

Aim. The work goal was to search more informative parameters of cytokine system for laboratory diagnosis in oncological and non-oncological pathology. Methods.The concentrations of some cytokines and chemokines (IL-4, ...
PI3K/mTOR-dependent signaling pathway as a possible regulator of processing body assembly

Gudkova, D.O.; Panasyuk, G.G.; Nemazanyy, I.O.; Filonenko, V.V. (Вiopolymers and Cell, 2011)

Aim. To study the role of PI3K/mTOR signaling pathway in regulation of processing body (PB) assembly. Methods. During this study we employed cell imaging technique and Western blot analysis. Results. It was shown that ...
Region-specific nitric oxide production in cytosolic and mitochondrial compartments of the rat brain tissues following chronic stress-induced depression-like behavior

Nazaryan, N.S.; Movsesyan, N.H.; Alchujyan, N.Kh.; Movsesyan, H.A.; Guevorkian, A.G.; Hairapetyan, H.L.; Barsegyan, K.A.; Kevorkian, G.A. (Вiopolymers and Cell, 2011)

Aim. To study subcellular nitrergic response in the rat brain regions following chronic stress-induced depression-like behavior. Methods. An animal model of depression induced by chronic circadian stress (CCS) established ...
Results on complex treatment of patients with glial tumors of brain with local chemotherapy

Harutyunyan, L.R. (Вiopolymers and Cell, 2011)

Aim. For the purpose of local chemotherapy in patients with malignant brain tumors after partial or total removal of tumors we used biodegradable film with methotrexate. The film, due to its properties, is firmly attached ...
Selective cytotoxicity and modification activity of picornaviruses on transformed cell lines

Karalyan, Z.A.; Avagyan, H.R. (Вiopolymers and Cell, 2011)

Aim. We do analyze of the dynamics of morphometabolic changes in transformed cells (of susceptoible lines) demonstrating resistance to picrnaviral infection. Methods. The study was performed by application of cell culture ...
Stimulation of transient versus sustained ERK1/2 phosphorylation by relative chitinase-like proteins CHI3L1 and CHI3L2 correlates with different kinase localization and biological outcome

Areshkov, P.O.; Avdieiev, S.S.; Iershov, A.V.; Kavsan, V.M. (Вiopolymers and Cell, 2011)

Aim. To determine 293 and U373 cell response and ERK1/2 activation profile after CHI3L1 or CHI3L2 treatment. Methods. Specific activation and localization of ERK1/2 kinases after CHI3L1 or CHI3L2 addition to unsupplemented ...
Treatment of lymphoid cells with the topoisomerase II poison etoposide leads to an increased juxtaposition of AML1 and ETO genes on the surface of nucleoli

Rubtsov, M.A.; Glukhov, S.I.; Allinne, J.; Pichugin, A.; Vassetzky, Y.S.; Razin, S.V.; Iarovaia, O.V. (Вiopolymers and Cell, 2011)

AML1 and ETO genes are known partners in the t(8,21) translocation associated with the treatment-related leukaemias in the patients receiving chemotherapy with DNA-topoisomerase II (topo II) poisons. Aim. To determine ...
Xanthine oxidase activity regulates human embryonic brain cells growth

Danielyan, K.E.; Kevorkian, G.A. (Вiopolymers and Cell, 2011)

Aim. Involvement of Xanthine Oxidase (XO; EC1.1.3.22) in cellular proliferation and differentiation has been suggested by the numerous investigations. We have proposed that XO might have undoubtedly important role ...

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