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Перегляд Experimental Oncology, 2012 (том 34) за назвою

Репозиторій DSpace/Manakin

Перегляд Experimental Oncology, 2012 (том 34) за назвою

Сортувати за: Порядок: Результатів:

  • 17-AAG mediates targeting of HSP90 limits tert activity in peritoneal sarcoma related malignant ascites by downregulating cyclin D1 during cell cycle entry 
    Chaklader, M.; Das, P.; Pereira, J.A.; Law, A.; Chattopadhyay, S.; Chatterjee, R.; Mondal, A.; Law, S. (Experimental Oncology, 2012)
    Aim: Peritoneal or retro-peritoneal sarcomatosis related malignant ascites formation is a rare but serious consequence of the locoregional metastatic event. The present work aimed to study the effect of the Hsp90 inhibitor ...
  • Abnormalities of apoptosis of the thyroid gland cells from extratumoral microfollicular tissue 
    Myshunina, T.M.; Kalinichenko, O.V.; Tronko, N.D. (Experimental Oncology, 2012)
    Aim: The aim of this study was to evaluate the frequency of existence of thyroid extratumoral normo- and microfollicular tissue in patients with thyroid carcinoma and peculiarities of apoptosis in mentioned tissue. Materials ...
  • Accelerated cellular senescence in solid tumor therapy 
    Wu, P.C.; Wang, Q.; Grobman, L.; Chu, E.; Wu, D.Y. (Experimental Oncology, 2012)
    Accelerated cellular senescence (ACS) is an emerging concept that implicates sustained, telomere-independent cell cycle arrest of neoplastic cells in response to chemotherapeutic agents, ionizing radiation, oxidative stress, ...
  • Accelerated rejection of the second transplants of immunogenic tumor in mice under inhibition of indoleamine 2,3-dioxygenase activity by ethyl pyruvate 
    Vasilyeva, E.D.; Kaledin, V.; Nikolin, V.P.; Popova, N.A.; Kirilyuk, I.A.; Grigor`ev, I.A. (Experimental Oncology, 2012)
    Aim: A recently discovered enzyme, indoleamine 2,3-dioxygenase (IDO), is expressed in placenta, dendritic cells and also in many kinds of tumors and in tumor-infiltrating macrophages. By catabolizing tryptophan, IDO causes ...
  • Anticancer therapy and apoptosis imaging 
    Yalcin, T.J.; Haimovitz-Friedman, A.; Verheij, M. (Experimental Oncology, 2012)
    Early response prediction is considered an essential tool to obtain a more customized anticancer treatment because it allows for the identification of patients who will benefit most from a particular therapy and prevents ...
  • Antitumor and adjuvant effects of phagelysates of E.coli in mice with Ehrlich carcinoma 
    Gambashidze, K.; Khorava, P.; Azaladze, T.; Kalandarishvili, K.; Jaiani, E.; Lasareishvil, B.; Azaladze, A.; Tediashvili, M. (Experimental Oncology, 2012)
    Aim: To augment anti-tumor host response and overcome the tumor-induced immunosuppression is of paramount importance especially when patient is subjected to radio-/chemotherapy and immune system suffers significantly. ...
  • Apoptosis in radiation therapy: a double-edged sword 
    Balcer-Kubiczek, E.K. (Experimental Oncology, 2012)
    Radiation therapy achieves its therapeutic effects by inducing apoptosis and non-apoptotic cell death. The aim of this focused review is to highlight the aspects of the cell death pathways most relevant to conventional ...
  • Cancer incidence and nuclear facilities in Ukraine: a community-based stydy 
    Bazyka, D.A.; Prysyazhnyuk, A.Ye.; Romanenko, A.Ye.; Fedorenko, Z.P.; Gudzenko, N.A.; Fuzik, M.M.; Khukhrianska, O.M.; Trotsyuk, N.K.; Gulak, L.O.; Goroch, Ye.L.; Sumkina, Ye.V. (Experimental Oncology, 2012)
    The study goal was to investigate malignant tumors incidence in 5 Ukrainian cities with nuclear hazardous enterprises: extractive, processing enterprises of uranium ore (Zhovti Wody and Dniprodzerzhynsk of Dnipropetrovsk ...
  • Cancer with unknown primary: finding a needle in a hay stack 
    Giesel, F.L.; Mehndiratta, A.; Mafomane, M.P.; Zechmann, C.M.; Bergmann, F.; Schemmer, P.; Haberkorn, U.; Kratochwil, C. (Experimental Oncology, 2012)
    Detection and resection of small neuroendocrine tumours (NET) is like finding a needle in a hay stack. Use of specific tracers such as 68Ga-DOTATOC in a PET/CT study has been proven to have a high sensitivity and specificity ...
  • Caspase-8 regulation of TRAIL-mediated cell death 
    Crowder, R.N.; El-Deiry, W.S. (Experimental Oncology, 2012)
    Research on TNF-related apoptosis-inducing ligand (TRAIL) and TRAIL receptors has advanced tremendously over the past 17 years. Initial observations of TRAIL and TRAIL receptor-mediated tumor cell toxicity led to enthusiasm ...
  • Caspase Control: Protagonists of Cancer Cell Apoptosis 
    Fiandalo, M.V.; Kyprianou, N. (Experimental Oncology, 2012)
    Emergence of castration-resistant metastatic prostate cancer is due to activation of survival pathways, including apoptosis suppression and anoikis resistance, and increased neovascularization. Thus targeting of apoptotic ...
  • c-FLIP, a master anti-apoptotic regulator 
    Safa, A.R. (Experimental Oncology, 2012)
    Cellular FLICE (FADD-like IL-1β-converting enzyme)-inhibitory protein (c-FLIP) is a master anti-apoptotic regulator and resistance factor that suppresses tumor necrosis factor-α (TNF-α), Fas-L, and TNF-related apoptosis-inducing ...
  • Chromosomal Radiosensitivity in Ukrainian breast cancer patients and healthy Individuals 
    Ryabchenko, N.M.; Glavin, O.A.; Shtefura, V.V.; Anikusko, M.F. (Experimental Oncology, 2012)
    Aim: Recent studies showed that increased chromosomal damage induced by ionizing radiation is observed among patients with different tumor types. The aim of the study was evaluation of chromosomal radiosensitivity in breast ...
  • Chronic lymphocytic leukemia 
    Kriachok, I.A. (Experimental Oncology, 2012)
  • Chronobiological approaches to antiangiogenic photodynamic therapy of tumors: the first experimental evaluatIon 
    Gamaleia, N.F.; Lisnyak, I.A.; Shishko, E.D.; Mamchur, A.A.; Prokopenko, I.V.; Kholin, V.V. (Experimental Oncology, 2012)
    In research of the last decade, rhythmic (circadian) variations of vascular endothelial growth factor (VEGF) production by tumors were discovered. The present paper authors have earlier synthesized and characterized a new ...
  • Clearing the final hurdles to mitochondrial apoptosis: regulation post cytochrome C release 
    Monian, P.; Jiang, X. (Experimental Oncology, 2012)
    In mammalian cells, the mitochondrial pathway of apoptosis plays a key role in various biological processes and has been extensively studied. One of the signature features of this pathway is permeabilization of the outer ...
  • Comparative study of dye-loaded liposome accumulation in sensitive and resistant human breast cancer cells 
    Yefimova, S.L.; Kurilchenko, I.Yu.; Tkacheva, T.N.; Rozhkov, V.A.; Sorokin, A.V.; Lukianova, N.Yu.; Bezdenezhnykh, N.A.; Malyukin, Yu.V.; Chekhun, V.F. (Experimental Oncology, 2012)
    The aim of this research is to study the dynamics and efficiency of liposome accumulation in sensitive and resistant human breast cancer cells. Methods: Methods of fluorescence microscopy, fluorescence microspectroscopy ...
  • Cytogenetic effects of neutron therapy in patients with parotid gland tumors and relapse of breast cancer 
    Melnikov, A.A.; Vasilyev, S.A.; Musabaeva, L.I.; Velikaya, V.V.; Gribova, O.V.; Startseva, Zh.A.; Urazova, L.N.; Lebedev, I.N.; Choynzonov, E.L. (Experimental Oncology, 2012)
    Aim:To assess the frequency and spectrum of chromosome aberrations and micronuclei in peripheral blood lymphocytes of patients with parotid salivary gland tumors and relapse of breast cancer during the course of neutron ...
  • Cytometry of apoptosis. Historical perspective and new advances 
    Wlodkowic, D.; Skommer, J.; Darzynkiewicz, Z. (Experimental Oncology, 2012)
    Characteristic changes in cell morphology paralleled by the appearance of a multitude of molecular and biochemical markers occur during apoptosis. These changes vary depending on the cell type, mechanism of induction of ...
  • Effects of combined sonodynamic and photodynamic therapies with photolon on a glioma C6 tumor model 
    Tserkovsky, D.A.; Alexandrova, E.N.; Chalau, V.N.; Istomin, Yu.P. (Experimental Oncology, 2012)
    The aim of this study was to investigate the low-power density sonication, sonodynamic therapy (SDT) with Photolon and combination of SDT and photodynamic therapy (PDT) with Photolon for the ablation of glioma C6 tumor ...

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