Перегляд за автором "Gout, I.T."

Результати 1-10 з 10

Application of serex-analysis for identification of human colon cancer antigens

Garifulin, O.M.; Kykot, V.O.; Gridina, N.Y.; Kiyamova, R.G.; Gout, I.T.; Filonenko, V.V. (Experimental Oncology, 2015)

Background: Colorectal, lung and breast tumors are the most devastating and frequent malignances in clinical oncology. SEREX-analysis of colon cancer leads to identification of more than hundred antigens which are potential ...
CoA Synthase influences adherence-independent growth and survival of mammalian cells in vitro

Breus, O.S.; Nemazanyy, I.O.; Gout, I.T.; Filonenko, V.V.; Panasyuk, G.G. (Вiopolymers and Cell, 2009)

Aims. We aimed to study the influence of the expression level, activity and subcellular localization of CoA Synthase (CoASy) on anchoring independent growth and viability of in vitro cultured cells. Methods. Abilities of ...
Generation and characterization of monoclonal antibodies specific to Coenzyme A

Malanchuk, O.M.; Panasyuk, G.G.; Serbyn, N.M.; Gout, I.T.; Filonenko, V.V. (Вiopolymers and Cell, 2015)

im. Generation of monoclonal antibodies specific to Coenzyme A. Methods. Hybridoma technique. KLH carrier protein conjugated with CoA was used for immunization. Screening of positive clones was performed with BSA conjugated ...
Generation and characterization of monoclonal antibodies specific to Coenzyme A

Malanchuk, O.M.; Panasyuk, G.G.; Serbyn, N.M.; Gout, I.T.; Filonenko, V.V. (Вiopolymers and Cell, 2015)

Aim. Generation of monoclonal antibodies specific to Coenzyme A. Methods. Hybridoma technique. KLH carrier protein conjugated with CoA was used for immunization. Screening of positive clones was performed with BSA conjugated ...
Identification of phosphate transporter NaPi2b as MX35 cancer antigen by modified SEREX approach

Kiyamova, R.G.; Gryshkova, V.S.; Usenko, V.S.; Khozaenko, Y.S.; Gurtovyy, V.A.; Yin, B.; Ritter, G.; Old, L.; Gout, I.T.; Filonenko, V.V. (Біополімери і клітина, 2008)

In this study we describe the identification of sodium-dependent phosphate transporter NaPi2b as MX35 cancer-associated antigen. To achieve this goal we have screened extensively a cDNA expressing library from ovarian ...
Identification of tumor-associated antigens in human thyroid papillar carcinoma

Rodnin, N.V.; Tykhonkova, I.O.; Kyyamova, R.G.; Garifulin, O.M.; Gout, I.T.; Filonenko, V.V. (Біополімери і клітина, 2003)

In this study two cDNA expressing libraries generated from thyroid papillar carcinomas were screened using SEREX approach. Thirty positive cDNA clones representing seventeen different genes were identified from both ...
Interaction of serine/threonine protein phosphatase 5 with the protein products of tumour suppressor gene Tsc2

Malanchuk, O.M.; Palchevskyy, S.S.; Pozur, V.K.; Gout, I.T.; Filonenko, V.V. (Біополімери і клітина, 2007)

Tuberous sclerosis (TSC) is a tumour disease caused by mutations in Tsc1 or Tsc2 genes. Both protein products of Tsc1 and Tsc2 form an intracellular complex possessing GTPase-activating (GAP) activity towards a small GTP ...
Intra- and intermolecular interactions mediated by adaptor protein Ruk/CIN85/SETA

Ilnytska, O.M.; Drel, V.R.; Shuvayeva, H.Yu.; Havrylov, S.V.; Fedyshyn, Ya.Ya.; Mayevska, O.M.; Ihumentseva, N.I.; Gout, I.T.; Buchman, V.L. (Біополімери і клітина, 2005)

Ruk/CIN85l SETA is a member of a separate and evolutionary conserved family of adapter I scaffold proteins implicated in apoptic and receptor tyrosine kinases signalling, rearrangement of actin cytoskeleton and cell adhesion, ...
Proline rich regions of coenzyme A synthase α and β interact with SH3 domains of signaling proteins in vitro

Breus, O.S.; Panasyuk, G.G.; Gout, I.T.; Filonenko, V.V.; Nemazanyy, I.O. (Біополімери і клітина, 2008)

Coenzyme A-synthases α and β (CoASy α and CoASy β ) contain proline rich regions which may bring them into complexes with SH3-domain containing proteins. To test whether CoASy isoforms can bind to SH3 domains we performed ...
Отримання рекомбінантного дефензину 1 сосни звичайної та його антифунгальна активність

Ковальова, В.А.; Гут, Р.Т.; Gout, I.T. (Біополімери і клітина, 2008)

Нещодавно нами очищено ендогенний дефензин із проростків сосни звичайної, а також клоновано кДНК, яка кодує дефензин 1 (PsDef1, Pinus sylvestris дефензин 1). Фрагмент кДНК дефензину 1, який кодує зрілу форму цього білка, ...

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Перегляд за автором "Gout, I.T."

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